 COA |
MSDS |
 HPLC |
NMR |
| CAS No: | 1421227-52-2 |
| Molecular formula(MF) | C28H30F3N7O3 |
| Molecular Weight(MW): | 569.58 |
| Alias |
| In vitro | DMSO | 100 mg/mL warmed (175.56 mM) |
|---|---|---|
| Ethanol | 80 mg/mL warmed (140.45 mM) | |
| Water | <1 mg/mL | |
| In vivo |
| Description | WS3 is a β cell proliferation inducer via modulation of Erb3 binding protein-1 (EBP1) and the IκB kinase pathway. | ||
|---|---|---|---|
| Targets |
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| In vitro |
WS3 induces proliferation of the mouse β cell line R7T1 with EC50 of 0.074 μM. [1] WS3 reversibly induces proliferation of primary fetal and adult human retinal pigment epithelial (RPE) cells. [2] |